Dental Caries Preventive Effect of Fluoride on the Inhibition of Glucose Fermentation
오윤종, 박정은, 김지은, 황경숙, 김효정, 권하정,
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오윤종 ( Oh Yoon-Jong ) - Kyung Hee University Department of Preventive and Social Dentistry
박정은 ( Park Jung-Eun ) - Kyung Hee University Department of Preventive and Social Dentistry
김지은 ( Kim Ji-Eun ) - Kyung Hee University Department of Preventive and Social Dentistry
황경숙 ( Hwang Kyung-Sook ) - Kyung Hee University Department of Preventive and Social Dentistry
김효정 ( Kim Hyo-Jeong ) - Andong Science College Department of Dental Hyigene
권하정 ( Kwon Ha-Jeong ) - Kyung Hee University Department of Preventive and Social Dentistry
KMID : 1157520130090020047
Abstract
Objective: The aim of this study was to confirm preventive affect of fluoride on the inhibition of glucose fermentation.
Methods: Saliva sample collected after intake of sugar from 36 volunteers. The saliva samples were stored in frozen after filtration. Sample was analyzed by ion chromatography using.
Results: When stored in room temperature, 95% of glucose was preserved in fluoride-mixed saliva, while only 65% of glucose was preserved without fluoride. Fluoride was not detected in the over half of subjects. The average fluoride concentration before sugar intake was higher than that after sugar intake. It is found that the fluoride concentration and lactic acid concentration before sugar intake showed negative correlation. The relationship between the fluoride concentration and produced lactic acid concentration after sugar intake was also investigated to negative correlation.
Conclusion: Fluoride inhibits carbohydrate metabolism and formation of lactic acid, and finally prevents dental caries.
키워드
fluoride; lactic acid; saliva; dental caries; ion chromatography
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